25. Identifying and Validating Recurrent Structural Variants Affecting Tumor Genomes using GROM and VN

…(graduate student), Dr. Andrey Grigoriev (faculty member) Introduction Structural variants (SVs), large genomic alterations, are often responsible for tumor development. Most studies focus on single-nucleotide variants (SNVs) and leave SVs aside. This project has addressed the disparity in analysis. Preview this research https://www.youtube.com/watch?v=Tun5yMUA-rw Click to view the research poster (PDF)…

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26. Effects of Chronic Pain on Seizure Susceptibility of Drosophila

…chronic pain and nonepileptic seizures by inducing nerve injury onto animal models, Drosophila melanogaster.Research Question: How does neuropathic chronic pain affect the susceptibility of seizures in pro-convulsiveDrosophila melanogaster?Hypothesis: Drosophila with nerve injury will have a higher duration of seizures. Preview this research https://www.youtube.com/watch?v=PMlYopK0sm4 Click to view the research poster (PDF)…

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27. Effects of exogenous diluted raw clover honey on drought tolerance in Arabidopsis thaliana

…Given that the diluted bee honey treatments produced the same biomass in less time than the control groups under drought stress, early results indicate that honey may prove to be sustainable, naturally available, and economically advantageous for agricultural use. Preview this research https://www.youtube.com/watch?v=b79HKJXLlB8 Click to view the research poster (PDF)….

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28. Effects of two SBT mutants on Arabidopsis Thaliana Phenotype

…of a SBT gene is confirmed, phenotypic analysis on root development, stomatal formation, and plant morphology and growth will be performed under normal condition and drought stress, to evaluate the function of the SBT gene in plant drought tolerance. Preview this research https://www.youtube.com/watch?v=FK41QEX6Tqk Click to view the research poster (PDF)…

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29. Optimizing Next Generation Chimeric Antigen Receptor (CAR) T-cell Therapy

…on ex vivo engineering of T cells. In vivo generation of CAR-or UIR- expressing T cells will further improve accessibility. Hypothesis: Usage of a targeted lentivirus that encodes for Universal Immune Receptors will improve the accessibility of CART therapy. Preview this research https://www.youtube.com/watch?v=DeVRPXu7OCc Click to view the research poster (PDF)…

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30. The Functions of Casein Kinase 1a Regarding Photoperiodism in Neurospora crassa

…repeat the experiment in order to replicate the data and generate new data with additional photoperiods. Understanding the mechanisms behind photoperiodism in N. crassa will provide insight in mechanisms behind circadian rhythms of a diverse eukaryotic organisms including humans. Preview this research https://www.youtube.com/watch?v=X-2pk0u47AI Click to view the research poster (PDF)…

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